Matt Damon (Jason Bourne), Franka Potente (Marie Helena Kreutz), Chris Cooper (Alexander Conklin), Clive Owen ('Der Professor'), Brian Cox (Ward Abbott), Adewale Akinnuoye-Agbaje (Nykwana Wombosi), Julia Stiles (Nicolette 'Nicky' Parsons), Gabriel Mann (Danny Zorn), Walton Goggins (Techniker), Josh Hamilton (Techniker), Nicky Naude ('Castel'), Tim Dutton (Eamon), David Bamber (Konsulatsangesteller), Anthony Green (Security Chief), Hubert Saint Macary (Leiter des Leichenschauhauses), Orso Maria Guerrini (Giancarlo), Denis Braccini (Picot), David Selburg (Marshall)