Matthew Broderick (Dr. Niko Tatopoulos), Jean Reno (Philippe Roaché), Maria Pitillo (Audrey Timmonds), Hank Azaria (Victor 'Animal' Palotti), Kevin Dunn (Colonel Hicks), Michael Lerner (Mayor Ebert), Harry Shearer (Charles Caiman), Arabella Field (Lucy Palotti), Vicki Lewis (Dr. Elsie Chapman), Doug Savant (Sergeant O'Neal), Malcolm Danare (Dr. Mendel Craven), Lorry Goldman (Gene - Assistent des Bürgermeisters), Christian Aubert (Jean-Luc), Philippe Bergeron (Jean-Claude), Frank Bruynbreoek (Jean-Pierre)