Trey Parker (Alien Singer / Biggest Douche Host #1 / The Biggest Douche in the Universe Announcer / Audience Member #8 / Alien #3 / Alien #2 / Audience Member #5 / Nelle McElroy / TV Producer / Man in Street #4 / Man in Street #1 / Scottish Pilot / John Edward / Trail), Matt Stone (Biggest Douche Host #2 / Quagmar / Audience Member #6 / Audience Member #4 / Thomas McElroy / Man in Street #3 / Man in Street #2 / Rob Schneider / Show Announcers / Butler / Audience Member #1 / Doctor #2 / The Ghost of Kenny / Kyle Broflovski), Jennifer Howell (Woman in Street #2), Mona Marshall (Woman in Street #3), Karin Perrotta (), Eliza Schneider (Audience Member #7 / Audience Member #6 / Audience Member #3 / Woman in Street #1 / Audience Member #2 / Audience Admission Woman / Female Pilot / Nurse #2 / Nurse #1 / Liane Cartman), Isaac Hayes (Chef), April Stewart (Sharon Marsh)